PHARMACEUTICAL EVALUATION OF THE RISKS OF THE USE OF NON-STEROID ANTI-INFLAMMATORIES Clara Paiva Lima, Heloisa Raquel de Oliveira Silva, Victoria Bernardo Pogian, Valter Garcia Santos

Abstract

Abstract : A class of non-steroidal anti-inflammatory drugs (NSAIDs) indicated for inflammatory processes that cause the most widely used type of drug in the world. A literature review was conducted to review the pharmacological aspects of NSAIDs, their imminent risks and highlight the importance of the pharmacist in contributing and rationalizing the use of medicines. Despite the insurance, the irrational uses of these drugs demonstrate several effects related to the mechanism of action. The risks found in the exacerbated use of NSAID were cerebrovascular, renal, hepatic, cardiovascular and thrombotic, gastrointestinal, gestational and fetal risks. Concluding that the prolonged and inappropriate use of the class brings risks to the health of an individual, this pharmaceutical mode can perform pharmacotherapeutic assistance with a safety purpose or rational use of medicines.